Diane-35 is not safe during pregnancy. This medication contains a combination of cyproterone and ethinylestradiol, which are not recommended for use during pregnancy due to their potential to cause harm to the developing fetus. Studies have shown that exposure to these components in the first trimester of pregnancy can increase the risk of certain birth defects.

It is crucial for women who are pregnant or planning to become pregnant to avoid using Diane 35 or any other medication containing similar components to ensure the safety of the unborn child. It is essential for pregnant women to consult their healthcare provider before taking any medication to prevent any potential risks to the pregnancy.

In conclusion, Diane-35 is not safe during pregnancy, and pregnant women should exercise caution and seek medical advice before taking any medications to protect the health and well-being of both themselves and their unborn child.